Publications | Verge Labs
Our published work.
Papers, preprints, and manuscripts from the Verge Labs team. Verge co-authors in bold.
Reports
Introducing vBx-1.0
Verge’s multi-modal foundation model for precision neurology
By Verge Labs
Published: June 16, 2026
Publications
| Year | Title / Venue / Authors | Program | Status |
|---|---|---|---|
| 2026 | Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB): A Translational Pharmacodynamic Biomarker for PIKfyve Inhibition With VRG50635 | ||
| Clinical and Translational Science · DOI 10.1111/cts.70489 | |||
| Gontier G, Kim G, Wang C, Zhu K, Gau R, Zhang N, Naphade S, Stewart A, Schmidt MJ, Galemmo R, Shook B, Tarachandani A, Choi I, Raines S, Scannevin RH, Grievink HW, Smits LMG, Kremer PHC, Cadavid D | ALS / VRG50635 | Published | |
| 2025 | Proof-of-concept study of the PIKfyve inhibitor VRG50635 in familial and sporadic ALS (Phase 1b) | ||
| Annals of Neurology (submitted Dec 2025) | |||
| Cadavid D, et al. (Verge VRG50635 team) | ALS / VRG50635 | In Submission | |
| 2025 | CD38 inhibition reduces inflammatory response and alters metabolism of activated primary human T cells | ||
| Frontiers in Immunology (submitted Oct 2025) | |||
| Heinrich L, Choi I, Scannevin RH, Dhara M | Obesity / VRG201 | In Submission | |
| 2024 | Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution | ||
| Molecular Neurodegeneration · DOI 10.1186/s13024-023-00699-0 | |||
| Martirosyan A, Ansari R, Pestana F, Hebestreit K, Ghosh H, Poovathingal S, Hadzhiev Y, Hadziahmetovic A, Cisterna A, Hardy J, Mighdoll M, Scannevin R, Kottick A, Hanson-Smith V, Guelfi S, et al. | Parkinson’s Disease | Published | |
| 2022 | Single-nucleus co-expression networks of dopaminergic neurons support iron accumulation as a plausible explanation to their vulnerability in Parkinson’s disease | ||
| bioRxiv (preprint) · DOI 10.1101/2022.12.13.514863 | |||
| Gómez-Pascual A, Martirosyan A, Hebestreit K, Mameffe C, Poovathingal S, Belgard TG, Altar CA, Kottick A, Holt M, Hanson-Smith V, Cisterna A, Mighdoll M, Scannevin R, Guelfi S | Parkinson’s Disease | Preprint | |
| 2022 | Systematic comparative analysis of strand-specific RNA-seq library preparation methods for low input samples | ||
| Scientific Reports (Nature Portfolio) · DOI 10.1038/s41598-021-04583-z | |||
| Naphade S, Bhatnagar R, Hanson-Smith V, Choi I, Zhang A | CONVERGE Platform | Published | |
| 2020 | A framework for integrating directed and undirected annotations to build explanatory models of cis-eQTL data | ||
| PLOS Computational Biology · DOI 10.1371/journal.pcbi.1007770 | |||
| Lamparter D, Bhatnagar R, Hebestreit K, Belgard TG, Zhang A, Hanson-Smith V | CONVERGE Platform | Published | |
| 2018 | Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons | ||
| Nature Medicine · DOI 10.1038/nm.4490 | |||
| Shi Y, Lin S, Staats KA, ..., Chen JA, Hanson-Smith V, Belgard TG, Zhang A, et al. | ALS / C9ORF72 | Published |